Salvia Officinalis

A number of double-blind, placebo-controlled, randomized, balanced-crossover studies in healthy humans have demonstrated improved memory, attention/executive function, alertness and mood following single doses of cholinesterase-inhibiting sage extracts or essential oils. A single, double-blind, placebo-controlled trial in a small cohort  of Alzheimer’s disease patients also demonstrated improved cognitive functioning and behavioral function (Clinical Dementia Rating) following a 16-week administration of a Salvia officinalis alcoholic tincture.Extracts of sage can enhance cognitive performance, comparable to the effect of the caffeine found in tea and coffee.